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Extracellular matrices

Elevate your offerings with custom ECMs

At Biomedical, our broad selection of extracellular matrices (ECMs) can be added to your portfolio with ease and efficiency. Regardless of your need, we can provide you with customizable thickness, strength and handling properties. On top of that, you can rely on the supply chain capabilities of a trusted global leader.

We work with partners worldwide to co-create ECM technology that supports patient healing – and bring progress to life

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Distinct tissues for customized handling

40+

Features in peer-reviewed articles

300k+

Procedures with Porcine Extracellular Matrices

Laboratory technicians in a medical clinic
Why our extracellular matrices?

Our solutions are naturally derived and manufactured through specialized processing techniques that preserve the inherent properties of native tissue. This provides an ideal environment for guided tissue regeneration, allowing you to effectively mimic natural tissue and promote seamless cellular integration for improved healing outcomes.

What are the types of devices that could be made using our extracellular matrices?  

  • Orthopedic: Osteoarthritis chondral resurfacing, meniscal repair, ligament and tendon repair/reconstruction, acromioplasty and subscapular spacers, bicep tenodesis, spinal dural repair.

  • Vascular: Heart valve components and structure heart repair. 

  • Tissue repair: Soft tissue reconstruction, wound care.  

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Portfolio overview

Discover our solutions for medical grade polyurethanes

 

ECM sheets

Our ECM sheet materials are ideal for soft tissue reconstruction. Their unique mechanical qualities also make them ideal for multiple applications. 

  • Based on porcine dermis, peritoneum, and pericardium sources.
  • Available in multiple thicknesses. 
  • Provided in bulk decellularized sheets or as packaged and/or sterilized materials.
Extracellular matrices sheet
Custom ECM forms

We can easily modify our custom ECM forms to work smoothly with your existing processes and materials. 

  • Available as multi-material constructs, in alternative sizes, shapes, and thicknesses.
  • Supported by additional downstream capabilities, including size reduction (milling).
ECM family
Custom development and manufacturing  

Our R&D experts can work with your tissues and processes through smooth production process transfers to co-create the ideal biologic scaffold.

  • This includes harvesting, cleaning, decellularization, disinfection, preservation, and sterilization of ECM materials.
  • Using other animal (non-human) tissue sources - including solid organs, tendons, bones, and nerves - for existing or new decellularization processing.
Extracellular matrices packaged
Application spotlight: Harnessing nature’s design with OPTRIX™ 

Our ECMs are available as a component material for your devices or as a finished product for distribution. All are treated with our OPTRIX™ process and designed to preserve the natural properties of the biomaterial. 

Frequently asked questions

Here are common questions that our experts get asked. Do you have a different question? Contact us.

DSM’s extracellular matrices contain collagen, but due to their gentle and selective processing, they also contain native growth factors, elastin, and other extracellular components. Collagen is broken down and rebuilt to create customized forms; while ECM’s processing preserves the strength and features of the native tissue.

Our extracellular matrix is primarily available in sheet form; however, the process can be applied to many tissue types. This enables us to work closely with partners, providing customized solutions to meet their needs.

dsm-firmenich Biomedical produces ECM using current Good Manufacturing Practices (cGMP) in ISO Class 8 Clean Rooms. For more information, please see our Quality & Certifications.

Technical resources

Looking for more information on how our ECM technology can help you tackle unmet needs?

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ECM Datasheet                                                           

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Medeor® Matrix Surgical Mesh                                         

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A long-term partner you can trust

We understand that medical product development can be a long, winding - and occasionally bumpy road. Rest assured that at dsm-firmenich Biomedical, we have the proven experience, capabilities, and knowledge to support you every step of the way. 

It starts with using a form-fit-function approach based on a comprehensive understanding of how the human body reacts to biomaterials following implantation. This in turn enables us to design materials that are compatible with the body’s physiology and help you develop finished products that can sustain, restore, and repair – all supported by applicable regulatory requirements. 

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MDSAP ISO 13485

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Contact us today to see how our products can help bring your idea to life. Our knowledgeable biomaterials team is here to assist you. Explore how we can collaborate to develop cutting-edge regenerative medicine and devices.
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