Prebiotic publications

Driving new research

Scientific research is key to our product offerings. We have over 20 years of experience in performing clinical trials and post-marketing studies, engaging in international, multidisciplinary collaborations across the globe to help build knowledge around our product concepts. Explore publications that support prebiotics below.

The impact of daily supplementation with rhamnogalacturonan-I on the gut microbiota in healthy adults: A randomized controlled trial

Ching Jian, Nikolaj Sorensen, René Lutter, Ruud Albers, Willem de Vos, Anne Salonen, Annick Mercenier
Biomed Pharmacother, 2024 May: 174:116561

A Novel Non-Digestible, Carrot-Derived Polysaccharide (cRG-I) Selectively Modulates the Human Gut Microbiota while Promoting Gut Barrier Integrity: An Integrated in Vitro Approach

Pieter Van den Abbeele, Lynn Verstrepen, Jonas Ghyselinck, Ruud Albers, Massimo Marzorati, Annick Mercenier
Nutrients, 2020 Jun 29;12(7): 1917

Consistent Prebiotic Effects of Carrot RG-I on the Gut Microbiota of Four Human Adult Donors in the SHIME® Model despite Baseline Individual Variability

Pieter Van den Abbeele, Cindy Duysburgh, Ilse Cleenwerck, Ruud Albers, Massimo Marzorati, Annick Mercenier
Microorganisms, 2021 Oct 13;9(10): 2142

The Dietary Intake of Carrot-Derived Rhamnogalacturonan-I Accelerates and Augments the Innate Immune and Anti-Viral Interferon Response to Rhinovirus Infection and Reduces Duration and Severity of Symptoms in Humans in a Randomized Trial

René Lutter, Annemarie Teitsma-Jansen, Esther Floris, Saeeda Lone-Latif, Abilash Ravi, Yanaika S Sabogal Pineros, Tamara Dekker, Barbara Smids, Ridha Khurshid, Marcela Aparicio-Vergara, Rianne Ruijschop, Lara Ravanetti, Wim Calame, Alwine Kardinaal, Ruud Albers
Nutrients, 2021 Dec 8;13(12): 4395

Effects of Dietary Supplementation with Carrot-Derived Rhamnogalacturonan-I (cRG-I) on Accelerated Protective Immune Responses and Quality of Life in Healthy Volunteers Challenged with Rhinovirus in a Randomized Trial

Sue McKay, Annemarie Teitsma-Jansen, Esther Floris, Tamara Dekker, Barbara Smids, Ridha Khurshid, Wim Calame, Alwine Kardinaal, René Lutter, Ruud Albers
Nutrients, 2022 Oct 12;14(20): 4258

Carrot RG-I Reduces Interindividual Differences between 24 Adults through Consistent Effects on Gut Microbiota Composition and Function Ex Vivo

Pieter Van den Abbeele, Stef Deyaert, Ruud Albers, Aurélien Baudot, Annick Mercenier
Nutrients, 2023 Apr 26;15(9): 2090

Associating structural characteristics to immunomodulating properties of carrot rhamnogalacturonan-I fractions

Krishna Desai, Justyna M Dobruchowska, Kari Elbers, Justyna Cybulska, Artur Zdunek, Mojtaba Porbahaie, Erik Jansen, Joost Van Neerven, Ruud Albers , Tom Wennekes, Annick Mercenier, Henk A Schols
Carbohydr Polym. 2025 Jan 1:347: 122730

Development of an Affordable, Sustainable and Efficacious Plant-Based Immunomodulatory Food Ingredient Based on Bell Pepper or Carrot RG-I Pectic Polysaccharides

Sue McKay, Paul Oranje, Jari Helin, Jean H Koek, Ellen Kreijveld, Pieter van den Abbeele, Ute Pohl, Gordana Bothe, Maria Tzoumaki, Marcela Aparicio-Vergara, Annick Mercenier, Henk Schols, Ruud Albers
Nutrients, 2021 Mar 16;13(3): 963

A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults

Ateequr Rehman, Susan M Tyree, Sophie Fehlbaum, Gillian DunnGalvin, Charalampos G Panagos, Bertrand Guy, Shriram Patel, Timothy G Dinan, Asim K Duttaroy, Ruedi Duss, Robert E Steinert
J Nutr. 2023 Jan;153(1): 96-105

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