Polyester Amide

• Significantly less frequent dosing
• Better adherence to therapy, potentially leading to fewer side effects and complications

• Hot melt extrusion, injection molding, or via solutions processing
• Potential for injectable microparticle formulations or as an implantable delivery form (fibers, larger rods, coating or films)
• Please contact us regarding any specific processing guidelines

• Compatible with challenging Active Pharmaceutical Ingredients (biologics, free amine small molecules, pH sensitive APIs)
• Controlled degradation – no pH drop (no acidification)
• Linear release of synthetic polymers - from multiple weeks to multiple months (>six-month data available for selected applications)
• Polyester amides and polyurethanes from DSM Biomedical have a long and proven clinical history

• Small molecules (hydrophilic, hydrophobic, salts, anti-inflammatory, steroids, anti-cancer, anaesthetics, prostaglandin analogs, kinase inhibitors)
• Biologics (peptides, proteins, and antibodies)

Pain management, metabolic disease management (Type II diabetes, obesity), non-alcoholic steatohepatitis (NASH), oncology, women’s health, cardiovascular, anti-psychotics, viral disease management (HIV, Hepatitis C); with others evaluated on a case-per-case basis.

We take different approaches, depending on the case (therapeutic area, type of partner).
Please contact us to learn more.

Yes, we do. Over the years we have accrued an enormous amount of knowledge and IP covering both the biocompatible polymers and processes used to create sustained release drug delivery solutions. For more information, contact us.