Human milk oligosaccharides publications

Oral supplementation of healthy adults with 2'-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota
Elison E, Vigsnaes LK, Rindom Krogsgaard L, Rasmussen J, Sørensen N, McConnell B, Hennet T, Sommer MO, Bytzer P.
The British Journal of nutrition, 2016 Oct;116(8): 1356-1368

Impact of 2'-Fucosyllactose on Gut Microbiota Composition in Adults with Chronic Gastrointestinal Conditions: Batch Culture Fermentation Model and Pilot Clinical Trial Findings
Ryan JJ, Monteagudo-Mera A, Contractor N, Gibson GR.
Nutrients, 2021 Mar 14;13(3): 938, doi: 10.3390/nu13030938

2'-fucosyllactose alone or combined with resistant starch increases circulating short-chain fatty acids in lean men and men with prediabetes and obesity
Canfora EE, Vliex LMM, Wang T, Nauta A, Bouwman FG, Holst JJ, Venema K, Zoetendal EG, Blaak EE
Frontiers in nutrition, 2023 Jul 17:10:1200645, doi:10.3389/fnut.2023.1200645, eCollection 2023

Oral supplementation of healthy adults with 2'-O-fucosyllactose and lacto-N-neotetraose is well tolerated and shifts the intestinal microbiota
Elison E, Vigsnaes LK, Rindom Krogsgaard L, Rasmussen J, Sørensen N, McConnell B, Hennet T, Sommer MO, Bytzer P.
Br J Nutr 2016 Oct; 116(8): 1356-1368

The Effects of Human Milk Oligosaccharides on Gut Microbiota, Metabolite Profiles and Host Mucosal Response in Patients with Irritable Bowel Syndrome
Iribarren C, Magnusson MK, Vigsnæs LK, Aziz I, Amundsen ID, Šuligoj T, Juge N, Patel P, Sapnara M, Johnsen L, Sørensen N, Sundin J, Törnblom H, Simrén M, Öhman L.
Nutrients 2021 Oct 27; 13(11): 3836. doi: 10.3390/nu13113836

Human Milk Oligosaccharides Support Normal Bowel Function and Improve Symptoms of Irritable Bowel Syndrome: A Multicenter, Open-Label Trial
Palsson OS, Peery A, Seitzberg D, Amundsen ID, McConnell B, Simrén M.
Clin Transl Gastroenterol 2020 Dec; 11(12): e00276

Novel therapies for Helicobacter pylori infection
Opekun AR, El-Zaimaity HM, Osato MS, Gilger MA, Malaty HM, Terry M, Headon DR, Graham DY. 
Aliment Pharmacol Ther 1999 Jan; 13(1): 35-42. doi: 10.1046/j.1365-2036.1999.00435.x.

Treatment of Helicobacter pylori infection using a novel antiadhesion compound (3'sialyllactose sodium salt). A double blind, placebo-controlled clinical study
Parente F, Cucino C, Anderloni A, Grandinetti G, Bianchi Porro G. 
Helicobacter 2003 Aug; 8(4): 252-6. doi: 10.1046/j.1523-5378.2003.00152.x.

Gastrointestinal Tolerance and Safety of 3’-Sialyllactose in Subjects Positive with Helicobacter pylori: A Pilot Study
Gurung, Woo, Cho, Hong, Kim
eCronicon.net

Randomized, triple-blind, placebo-controlled study to evaluate the safety of 6'-Sialyllactose in healthy adults
Kim JH, Yong SY, Kim SH, Baek A, Go TH, Kang DR.
Regul Toxicol Pharmacol 2022 Mar: 129:105110.

Human Milk Oligosaccharides Modulate Fecal Microbiota and Are Safe for Use in Children With Overweight: A Randomized Controlled Trial
Fonvig CE, Amundsen ID, Vigsnæs LK, Sørensen N, Frithioff-Bøjsøe C, Christiansen M, Hedley PL, Holm LA, McConnell B, Holm JC. 
J Pediatr Gastroenterol Nutr. 2021 Sep 1; 73(3): 408-414.